YOUR GUT AND CANCER PREVENTION AND IMPROVING OUTCOME OF CANCER TREATMENT

Bacteria and Longer Survival

Regarding the development of cancer and preventing effective cancer treatment due to ‘bad’ gut bacteria, are you the considering the increased  consumption of fruits and vegetables to boost ‘good’ gut bacteria and development of natural cancer fighting T-cells?

 

Anti-inflammatory health beneficial gut bacteria can slow or stop the development of some cancers and can aid in cancer treatment as far as transplanting fecal matter (poop) with good  gut bacteria from one patient to another patient.  "The article in CURE Cancer Updates, Research and Education 'Gut Reaction CURE IMMUNO ONCOLOGY in  issue 06.18.People with so-called 'good' gut bacteria and a more diverse mix of gut bacteria respond better to immunotherapy.  People’s microbiomes can be changed through diet, exercise, antibiotics, or probiotic use of transplantation of fecal material.

 

Good Poop is Hard to Find

Newsweek September 2017 included an article about the call for more healthy vegans to consider becoming stool super donors (i.e., providing specimens on a regular basis) to serve the growing demand since fecal microbiota transplant is now considered the gold standard for treating recurrent Clostridium difficile (C. difficile) infections and other potentially life-threatening gastrointestinal illnesses. In this experimental medical procedure, stool from a healthy person is transplanted to the gut of an ailing patient either in encapsulated pill form or through a colonoscopy. 

 

Good Gut Bacteria Make You Live Longer?

A study published in The New England Journal of Medicine found that 81 percent of patients with C. difficile who underwent transplantation of fecal material made a full recovery from their illness. Research since has shown the cure rate after follow-up transplants may be even higher, as much as 90 percent. ( Lymphoma formed only half as quickly as it did in mice receiving good gut bacteria in addition, mice with good bacteria lived four times longer and had less DNA damage and inflammation.

 

Building a Better Gut

Small organic molecules called short-chain fatty acids (SCFA) are produced when the fibre in our fruit and vegetables is fermented by our resident microbes.

Fruits and vegetables are key to producing SCFA’s SCFA’s help regulate crotonylations. "Short chain fatty acids are a key energy source for cells in the gut but we've also shown they affect crotonylation of the genome," says lead author Rachel Fellows from Babraham Institute.(https://www.babraham.ac.uk/news/2018/01/how-good-bacteria-control-your-genes)

Specifically, SCFAs produced by the kinds of bacteria found in a healthy human colon promote crotonylation by preventing an enzyme called histone deacetylase 2 (HDAC2) from removing the markers. Crotonylations can switch protein genes on and off.  High number of HDAC2 proteins may raise the risk of colorectal cancer.

 

A comprehensive review of thousands of studies on diet, physical activity, and weight conducted for the World Cancer Research Fund and the American Institute for Cancer Research pointed to the benefits of eating mostly foods of plant origin. Foods such as broccoli, berries, and garlic showed some of the strongest links to cancer prevention

Large studies in England and Germany showed that vegetarians were about 40 percent less likely to develop cancer compared to meat eaters.

 

The World Health Organization has determined that dietary factors account for at least 30 percent of all cancers in Western countries and up to 20 percent in developing countries. When cancer researchers started to search for links between diet and cancer, one of the most noticeable findings was that people who avoided meat were much less likely to develop the disease.

 

Bringing Home the 'Bacon' 

Bacon, ham and sausages rank alongside cigarettes as a major cause of cancer, the World Health Organization has said, placing cured and processed meats in the same category as asbestos, alcohol, arsenic and tobacco. The report from the WHO’s International Agency for Research on Cancer said there was enough evidence to rank processed meats as group 1 carcinogens because of a causal link with bowel cancer. It places red meat in group 2A, as “probably carcinogenic to humans”. Eating red meat is also linked to pancreatic and prostate cancer, the IARC says. The World Cancer Research Fund has long been advising people that processed meat is a cancer hazard. It advises eating products such as ham, bacon and salami as little as possible and having no more than 500g a week of red meat, including beef, pork and lamb. Bringing Home the 'Kale' is a Much Better Choice!

 

The July/August issue IDEA/ACE Fitness Journal states explains that the gastrointestinal tract and the enteric nervous system are a rich source of hormones that perform critical functions. Among the hormones , the best known are insulin and glucagon, which control blood sugar homeostasis (balance). Many other hormones play significant roles in metabolism, gut physiology, appetite, fay deposition, and weight control. The enteric nervous system, neurotransmitters and gut hormones are intimately involved with the gut immune system, microbiome and diet. The gut is where 90% of immune system activity takes place. Gut bacteria affect brain function, the enteric and central nervous systems, serotonin production, affect obesity, cardiovascular disease, immune system. 

 

We know that lifestyle changes may influence gut microbiome to an extend not previously recognized. Doing your research in disease prevention, boosting your metabolism and fighting disease and aiding treatment of the disease may add many more good years to your life. Changing your lifestyle can be achieved and seeking out the help of a Accredited ACE Health Coach may provide your with needed support to do so.

 

References:

https://www.newsweek.com/peta-vegans-poop-stool-fecal-transplant-661364)

(https://www.pcrm.org/health/cancer-resources/diet-cancer/facts/meat-consumption-and-cancer-risk)

(https://www.theguardian.com/society/2015/oct/26/bacon-ham-sausages-processed-meats-cancer-risk-smoking-says-who)

Understanding the human microbiome July- August 2018 Fitness Journal

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